Leigh Marcus Selected Research

Multiple Endocrine Neoplasia Type 2b (MEN 3)

1/2015	Patterns of thyroid hormone levels in pediatric medullary thyroid carcinoma patients on vandetanib therapy.
8/2013	Vandetanib in children and adolescents with multiple endocrine neoplasia type 2B associated medullary thyroid carcinoma.

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Leigh Marcus Research Topics

Disease

6	Neoplasms (Cancer) 01/2021 - 01/2012
3	Fatigue 01/2021 - 04/2015
3	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 06/2017
3	Thyroid Neoplasms (Thyroid Cancer) 01/2015 - 02/2012
2	Diarrhea 01/2021 - 06/2017
2	Microsatellite Instability 01/2021 - 01/2019
2	Nausea 01/2021 - 06/2017
2	Asthenia 01/2021 - 06/2017
2	Brain Neoplasms (Brain Tumor) 04/2015 - 01/2012
2	Multiple Endocrine Neoplasia Type 2b (MEN 3) 01/2015 - 08/2013
1	Cholangiocarcinoma 01/2023
1	Toxic Optic Neuropathy 01/2023
1	Hyperphosphatemia 01/2023
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 11/2022
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 11/2022
1	Heart Failure 01/2021
1	Vision Disorders (Hemeralopia) 01/2021
1	Hyperuricemia 01/2021
1	Hematologic Neoplasms (Hematological Malignancy) 09/2020
1	Leukemia 09/2020
1	Lymphoma (Lymphomas) 09/2020
1	Thrombocytopenia (Thrombopenia) 06/2017
1	Neutropenia 06/2017
1	Vomiting 06/2017
1	Fever (Fevers) 06/2017
1	Abdominal Pain (Pain, Abdominal) 06/2017
1	Anemia 06/2017
1	Febrile Neutropenia 06/2017
1	Headache (Headaches) 04/2015
1	Hypothyroidism 01/2015
1	medullary Thyroid cancer 01/2015
1	Neoplasm Metastasis (Metastasis) 02/2012

Drug/Important Bio-Agent (IBA)

3	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2019
3	pembrolizumabIBA 01/2021 - 01/2019
2	Irinotecan (Camptosar)FDA LinkGeneric 01/2019 - 06/2017
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2019 - 06/2017
2	PlatinumIBA 04/2015 - 01/2012
2	satraplatin (JM 216)IBA 04/2015 - 01/2012
2	vandetanib (ZD6474)IBA 01/2015 - 08/2013
1	pemigatinibIBA 01/2023
1	Etoposide (VP 16)FDA LinkGeneric 11/2022
1	NucleosidesIBA 11/2022
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 11/2022
1	Plant NectarIBA 11/2022
1	nelarabine (506U78)FDA Link 11/2022
1	tyrosine receptor (receptor, tyrosine)IBA 01/2021
1	entrectinibIBA 01/2021
1	Phosphotransferases (Kinase)IBA 01/2021
1	PanobinostatIBA 09/2020
1	A 7 (A-7)IBA 01/2019
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2017
1	trifluridine tipiracil drug combinationIBA 06/2017
1	ElectrolytesIBA 04/2015
1	EnzymesIBA 04/2015
1	Thyroid HormonesIBA 01/2015
1	Thyroxine (Levothyroxine)FDA LinkGeneric 01/2015
1	indium-111-octreotideIBA 02/2012
1	Somatostatin Receptors (Somatostatin Receptor)IBA 02/2012
1	Cisplatin (Platino)FDA LinkGeneric 01/2012

Therapy/Procedure

4	Therapeutics 01/2023 - 01/2015
2	Drug Therapy (Chemotherapy) 06/2017 - 01/2015
1	Biological Therapy 06/2017
1	Drug Tapering 06/2017
1	Thyroidectomy 01/2015